Hematology Critical Care


Hébert P, Wells G, Blajchmann M, et al. A multicenter randomized controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:409-17. Landmark study found equal mortality using transfusion thresholds of 7 gm/dl and 10gm/dl and higher mortality with liberal transfusion among younger and less ill patients.
PMID: 9971864
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Sickle Cell Anemia:

Novelli EM and Gladwin MT. Crises in sickle cell disease. Chest. 2016; 149:1082-93. A review that includes discussion of acute chest syndrome, acute anemia, stroke, and infectious complications.
PMID: 26836899
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